Clinical tool · educational

Drug Interaction Checker

Check medicines for known interactions and understand what they may mean, how serious they may be, and what monitoring or professional advice may be relevant.

Interaction information is educational and does not replace advice from a doctor, pharmacist, or other qualified healthcare professional.

Before you use this tool. This checker cannot account for your doses, medical history, kidney or liver function, pregnancy, allergies or every product on the market. It shows what the cited official sources say about a pair of medicines; it does not decide whether a combination is right for you.

Add your medications

Search by generic name, brand name, or active ingredient. Add at least two medications to begin.

Examples:

Check two or more medications

Add the medicines you want to compare. We’ll review each medication pair for known interactions in our available clinical data.

Try an example

Warfarin + IbuprofenLosartan + IbuprofenAmlodipine + SimvastatinLisinopril + Losartan

Examples are pairs with a sourced record in the current dataset.

How the checker works

  1. Names become ingredients. A brand name maps to its generic medicine; a combination product (for example co-codamol) is split into each active ingredient; a named substance without a page on this site is matched by name.
  2. Every pair is checked. For the medicines you add, every unique pair is compared against the sourced interaction records: medicine–medicine records, records written for a whole drug class (applied only to its members, as the source states), and duplicate ingredients or therapeutic duplication.
  3. Severity comes from the source. Each record carries the state its cited document's wording supports (contraindicated, avoid, specialist supervision, monitor or adjust, documented); the checker maps those states onto its display tiers and never grades an interaction from its own reading. Nothing is labelled minor by inference.
  4. Results are shown highest severity first, then the pairs with no known interaction in the available data, the related anatomy, tests and classes, and every source used.

About our interaction data

Source
BNF (NICE), NHS, MedlinePlus (NIH), NICE, UK Government, paraphrased into records that each cite the document and section they came from
Coverage
72 interaction records · 39 medicines with pages · 14 brand and combination products · 73 named substances · 27 drug classes
Last updated
Review status
Facts checked against the cited sources; not yet clinically reviewed

The checker can detect medicine-to-medicine interactions recorded in the official information of the medicines represented on this site, duplicate active ingredients across brands and combination products, and therapeutic duplication within a drug class where official guidance advises against the combination. It cannot detect interactions that are not in the dataset, interactions with food, alcohol, supplements, diseases, pregnancy, allergies or laboratory tests, or the effect of a particular dose, route, age or kidney and liver function. Interaction databases differ from one another; a pair that is not found here may still interact.

Learn how Anatomy Nexus reviews medication information · Medical review policy · References policy

Medical information notice: This checker is for education and general information only. It may not include every possible interaction and cannot account for your full medical history, doses, laboratory results, allergies, pregnancy status, kidney or liver function, or other individual factors. Do not start, stop, or change a medicine based only on this tool. Ask a doctor or pharmacist for personal medication advice.