Medication · Respiratory

Inhaled corticosteroids

Also known as: preventer inhaler, brown inhaler, ICS, steroid inhaler

The preventer inhalers of asthma: low doses of steroid delivered straight into the airways damp down inflammation so attacks become rarer and milder.

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Generic name
Inhaled corticosteroids
Active ingredient
Inhaled corticosteroids
Product type
Small-molecule medicine
Drug class
Corticosteroids
Brand names
UK Pulmicort, Flixotide · US Flovent, Pulmicort Flexhaler
Routes
Inhaled, Nebulised
Dosage forms
Metered-dose inhaler, Dry-powder inhaler, Nebuliser solution
Also known as
preventer inhaler, brown inhaler, ICS, steroid inhaler
Forms
Metered-dose and dry powder inhalers, usually twice daily; combination products with formoterol or salmeterol; nebulised budesonide in children
Onset and duration
Symptoms improve over 1-2 weeks; full effect at 4-8 weeks.
Terminology
ATC R03BA
Monitoring
Symptom control, reliever use, peak flow; growth in children; annual review.

Availability by country

CountryStatusNoteSource
UKPrescription only UK

Legal status differs between countries and can change; each row cites the document it was taken from and applies only to the country named.

What it is used for

  • The cornerstone of asthma treatment: daily to prevent attacks and control symptoms
  • COPD with frequent exacerbations and high blood eosinophils, combined with long-acting bronchodilators
  • Combined inhalers with formoterol used as both preventer and reliever (MART regimens)

How it works in the body

Steroid molecules deposited on the airway lining diffuse into cells and bind glucocorticoid receptors, which move to the nucleus and switch off the genes for inflammatory cytokines, reduce eosinophils and mast cells, and shrink mucosal swelling and mucus. Inhaling delivers a tiny dose straight to the airways, so the whole-body effects of steroid tablets are largely avoided. Benefit builds over days to weeks and depends on daily use.

Common side effects

  • Oral thrush and hoarse voice (rinse the mouth and use a spacer)
  • Sore throat, cough on inhaling

Serious: seek help

  • Pneumonia risk in COPD at higher doses
  • At high doses long term: adrenal suppression, reduced bone density, cataract and glaucoma, easy bruising, a small effect on growth in children
  • Sudden stopping of high doses can unmask adrenal insufficiency

Cautions and interactions

  • Use the lowest dose that keeps control, stepped up or down at review
  • Long-acting beta agonists must never be used alone in asthma without a steroid
  • Carry a steroid card at high doses; check bone density if on high dose for years
  • Technique check at every review

Interactions

Check interactions

Taking Inhaled corticosteroids with other medicines? Add them to the checker to see what the official sources say about each pair: the mechanism, general management and monitoring, never a bare "safe".

Check Inhaled corticosteroids interactions

Interactions documented in the official sources cited on each card. The list covers the medicines represented on this site and is not exhaustive; how the interaction data is compiled.

No pair records for this medicine are in the sources currently represented by Anatomy Nexus. Absence from this list does not mean no interaction exists.

As a member of Corticosteroids

Records written for the whole corticosteroids class apply to Inhaled corticosteroids.

Metformin + Corticosteroids (class)

Severity not gradedInteraction documented

Systemic corticosteroids raise blood glucose and can reduce diabetes control on metformin.

Why it can occur
pharmacodynamic antagonism
What official information says
UK information lists steroid tablets among medicines that affect blood sugar.
What to discuss with a clinician
Documented; glucose monitoring during and after a steroid course.
What may be monitored
Blood glucose · Blood glucose
Basis of the status
NHS: Taking metformin with other medicines (tell your doctor)
Sources
BNF: Metformin interactions (Interactions) UK
NHS: Metformin (Taking it with other medicines and herbal supplements · Medicines that interact with metformin) UK
Review
Facts checked against the cited sources; not yet clinically reviewed · last reviewed 12 September 2026

Medicines in this group

beclometasonebudesonidefluticasonemometasoneciclesonide

Inhaled corticosteroids is a group of related active ingredients; each is a distinct medicine.

Same-class and related medicines

Same class: Corticosteroids

Beclometasone (inhaled)Prednisolone and steroidsbeclometasonebudesonidedexamethasonefluticasonehydrocortisonemethylprednisoloneprednisoloneprednisone

Medicines that share the class of Inhaled corticosteroids. They are separate medicines with their own licences, doses and interactions, not alternative names for Inhaled corticosteroids.

Related medicines

Medicines often discussed alongside Inhaled corticosteroids: used together, compared with it, or acting on the same problem by a different route.

Educational content. Anatomy Nexus provides medical education and does not replace professional medical advice, diagnosis, treatment, prescribing or pharmacist review. Doses, choices and monitoring are decided by a prescriber for an individual; never start, stop or change a medicine on the basis of this page.