Medication · Respiratory

Salbutamol

Also known as: albuterol, reliever inhaler, blue inhaler

The blue reliever inhaler: a short-acting beta-2 agonist that opens the airways within minutes to relieve asthma and COPD symptoms during an attack or before exercise.

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Generic name
Salbutamol
Active ingredient
Salbutamol (variants: salbutamol sulfate)
Product type
Small-molecule medicine
Drug class
Bronchodilators
Brand names
UK Ventolin, Salamol, Airomir · US ProAir, Ventolin HFA, Proventil
Routes
Inhaled, Nebulised, Oral, Intravenous
Dosage forms
Metered-dose inhaler, Dry-powder inhaler, Nebuliser solution, Tablet, Syrup, Injection
Also known as
albuterol, reliever inhaler, blue inhaler
Forms
Pressurised metered-dose inhaler 100 micrograms per puff (best with a spacer), dry powder inhaler, nebuliser solution, tablets and syrup (rarely), intravenous
Onset and duration
Within 5 minutes, peak 15-30 minutes, lasts 4-6 hours.
Terminology
RxNorm RxCUI 435 · ATC R03AC02 · FDA EPC beta2-Adrenergic Agonist [EPC]
Monitoring
Peak flow and symptom diary; frequency of use as a marker of control.

Availability by country

CountryStatusNoteSource
UKPrescription only UK

Legal status differs between countries and can change; each row cites the document it was taken from and applies only to the country named.

What it is used for

  • Relief of wheeze and breathlessness in asthma and COPD ('reliever')
  • Before exercise in exercise-induced asthma
  • Nebulised or intravenous in severe asthma attacks and COPD flares
  • Lowering high potassium in emergencies (nebulised)

How it works in the body

Stimulates beta-2 adrenergic receptors on the smooth muscle wrapped around the bronchi. This raises cyclic AMP inside the muscle cells, relaxing them within minutes so the airways widen and air moves more freely. It relieves the narrowing but does nothing for the underlying inflammation, which is why needing it more than twice a week signals poorly controlled asthma and the need for a preventer.

Common side effects

  • Fine tremor, fast heartbeat, palpitations, headache
  • Feeling shaky or restless; muscle cramps

Serious: seek help

  • Low potassium with high doses (with steroids, diuretics, theophylline)
  • Arrhythmias in people with heart disease at high doses
  • Paradoxical bronchospasm (rare); over-reliance masking worsening asthma, linked to asthma deaths

Cautions and interactions

  • Using more than three canisters a year, or needing it daily, means the asthma plan needs review
  • Anti-inflammatory reliever (budesonide-formoterol) is now preferred as the sole reliever in many guidelines
  • Inhaler technique matters: slow deep breath, hold for 10 seconds; spacers for children and during attacks
  • Beta blockers antagonise the effect

Interactions

Check interactions

Taking Salbutamol with other medicines? Add them to the checker to see what the official sources say about each pair: the mechanism, general management and monitoring, never a bare "safe".

Check Salbutamol interactions

Interactions documented in the official sources cited on each card. The list covers the medicines represented on this site and is not exhaustive; how the interaction data is compiled.

No pair records for this medicine are in the sources currently represented by Anatomy Nexus. Absence from this list does not mean no interaction exists.

Same-class and related medicines

Same class: Bronchodilators

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Medicines that share the class of Salbutamol. They are separate medicines with their own licences, doses and interactions, not alternative names for Salbutamol.

Related medicines

Medicines often discussed alongside Salbutamol: used together, compared with it, or acting on the same problem by a different route.

Educational content. Anatomy Nexus provides medical education and does not replace professional medical advice, diagnosis, treatment, prescribing or pharmacist review. Doses, choices and monitoring are decided by a prescriber for an individual; never start, stop or change a medicine on the basis of this page.